Research progress on acarbose analogues

ZHANG Hongzhi, XU Qingyang

doi:10.16774/j.cnki.issn.1674-2214.2015.02.013

Bulletin of Fermentation Science and Technology >

2015 , Vol. 44 >Issue 2: 46 - 51

DOI: https://doi.org/10.16774/j.cnki.issn.1674-2214.2015.02.013

Research progress on acarbose analogues

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College of Biotechnology, Tianjin University of Science and Technology, Tianjin 300457, China

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Abstract

Glucosidase inhibitors are specific drugs for type II diabetes mellitus (Non-insulin dependent diabetes mellitus, NIDDM). In order to provide theoretical basis for the fermentation of acarbose and its analogues. This paper summarized the research progress in their biosynthetic pathways, transport pathways and fermentation process optimization.

Key words： acarbose analogue; biosynthesis pathway; transport pathway; fermentation process control

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ZHANG Hongzhi, XU Qingyang . Research progress on acarbose analogues[J]. Bulletin of Fermentation Science and Technology, 2015 , 44(2) : 46 -51 . DOI: 10.16774/j.cnki.issn.1674-2214.2015.02.013

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