系统生物学研究手段包括基因组学、转录组学、代谢组学、蛋白组学和通量组学等，可以获得研究对象整体代谢途径、调控网络的信息． 将组学技术应用于氨基酸的发酵菌株优化过程，可以为菌株的进一步代谢工程改造提供信息基础与理论指导． 介绍各种组学技术在氨基酸微生物发酵研究中的应用与发展趋势，通过综合运用各种组学数据信息，可以更好地指导氨基酸发酵优良菌株的理性设计与构建．

Omics technology，including genomics，transcriptomics，metabolomics，proteomics，etc，can be used to acquire the whole metabolic pathway information and regulatory network information of the research objects． The application of omics technology to the optimization of amino acid fermentation provides important theoretical guidance for further metabolic engineering of microorganisms with enhanced production of target products． This paper introduces the application and development trend of omics techniques applied in microbial fermentation of amino acids，which is conducive to the rational design and construction of excellent amino acid production strains．